Gather all your ingredients including the butternut squash, ground turkey, olive oil, and seasonings.

Preheat the oven to 400°F (200°C).

Peel and dice the butternut squash. In a large bowl, combine it with olive oil, garlic powder, onion powder, salt, and pepper. If desired, add dried thyme.

Spread the coated squash on a baking sheet in a single layer. Roast in the oven for about 25-30 minutes until tender and caramelized.

While the squash roasts, heat a skillet over medium heat. Add the ground turkey and cook until browned, about 7-10 minutes, breaking it apart as it cooks. Season with salt and pepper.

Once the butternut squash is done, add it to the skillet with the cooked turkey, stir well, and let it heat through.

Serve warm, optionally sprinkled with Parmesan cheese.